Description

Drug concentrations in body fluids, typically plasma, can be monitored therapeutically to aid in diagnosis and throughout treatment. The choice of medications for therapeutic drug monitoring is crucial because many drugs' concentrations and effects are not directly correlated. Therapeutic drug monitoring tries to improve pharmacological efficacy, lessen toxicity, or help with diagnosis for a limited group of pharmaceuticals. It has intrinsic restrictions despite its apparent advantages. Patients must be given pharmaceuticals that are appropriate for their clinical needs, in doses that fit their unique requirements, for an adequate amount of time, and at the least expensive cost to them and their community in order for medication to be used rationally. Medication concentrations are measured as part of therapeutic medication monitoring, but the results are also clinically interpreted. Once a molecule has been found that satisfies all of these criteria, medication development will start before clinical trials. Computer-aided drug design may be used in one or more of these processes, although it is not required. For practising physicians, large practises, and students interested in learning about practical pharmacology, Applied Therapeutics is a significantly more effective instructional material. The reader is guided through the fundamentals of pharmacological therapy in this text.